Post by Master Kim on Jan 29, 2015 17:53:34 GMT -5
Vitiligo - en.wikipedia.org/wiki/Vitiligo
Vitiligo /ˌvɪtɨˈlaɪɡoʊ/ is a chronic skin disease characterized by portions of the skin losing their pigment. It occurs when skin pigment cells die or are unable to function. Aside from cases of contact with certain chemicals, the cause of vitiligo is unknown. Research suggests vitiligo may arise from autoimmune, genetic, oxidative stress, neural, or viral causes. Vitiligo is typically classified into two main categories: segmental and non-segmental vitiligo.
The global incidence of vitiligo is less than 1%, with some populations averaging between 2-3% and as high as 16%. Autoimmune diseases such as Addison's disease, Hashimoto's thyroiditis, and type 1 diabetes mellitus tend to occur more often in people who have vitiligo. There is no cure for vitiligo but many treatment options are available including topical steroids, calcineurin inhibitors, and phototherapy.
Left: Vitiligo of the hand in a person with dark skin.
Right: Vitiligo on lighter skin
Signs and symptoms
The only sign of vitiligo is the presence of pale patchy areas of depigmented skin which tend to occur on the extremities. The patches are initially small, but often grow and change shape. When skin lesions occur, they are most prominent on the face, hands and wrists. The loss of skin pigmentation is particularly noticeable around body orifices, such as the mouth, eyes, nostrils, genitalia and umbilicus. Some lesions have increased skin pigment around the edges. Patients who are stigmatized for their condition may experience depression and similar mood disorders.
Vitiligo /ˌvɪtɨˈlaɪɡoʊ/ is a chronic skin disease characterized by portions of the skin losing their pigment. It occurs when skin pigment cells die or are unable to function. Aside from cases of contact with certain chemicals, the cause of vitiligo is unknown. Research suggests vitiligo may arise from autoimmune, genetic, oxidative stress, neural, or viral causes. Vitiligo is typically classified into two main categories: segmental and non-segmental vitiligo.
The global incidence of vitiligo is less than 1%, with some populations averaging between 2-3% and as high as 16%. Autoimmune diseases such as Addison's disease, Hashimoto's thyroiditis, and type 1 diabetes mellitus tend to occur more often in people who have vitiligo. There is no cure for vitiligo but many treatment options are available including topical steroids, calcineurin inhibitors, and phototherapy.
Left: Vitiligo of the hand in a person with dark skin.
Right: Vitiligo on lighter skin
Signs and symptoms
The only sign of vitiligo is the presence of pale patchy areas of depigmented skin which tend to occur on the extremities. The patches are initially small, but often grow and change shape. When skin lesions occur, they are most prominent on the face, hands and wrists. The loss of skin pigmentation is particularly noticeable around body orifices, such as the mouth, eyes, nostrils, genitalia and umbilicus. Some lesions have increased skin pigment around the edges. Patients who are stigmatized for their condition may experience depression and similar mood disorders.
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